Circular RNA cVIM promotes hepatic stellate cell activation in liver fibrosis via miR-122-5p/miR-9-5p-mediated TGF-β signaling cascade

Abstract Hepatic stellate cell (HSC) activation is considered as a central driver of liver fibrosis and effective suppression of HSC activation contributes to the treatment of liver fibrosis. Circular RNAs (circRNAs) have been reported to be important in tumor progression. However, the contributions...

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Bibliographic Details
Main Authors: Zhenxu Zhou, Rongrong Zhang, Xinmiao Li, Weizhi Zhang, Yating Zhan, Zhichao Lang, Qiqi Tao, Jinglu Yu, Suhui Yu, Zhengping Yu, Jianjian Zheng
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05797-3