Protective interaction of human phagocytic APC subsets with Cryptococcus neoformans induces genes associated with metabolism and antigen presentation

Protective interaction of human phagocytic APC subsets with Cryptococcus neoformans induces genes associated with metabolism and antigen presentation

Cryptococcal meningitis is the most common cause of meningitis among HIV/AIDS patients in sub-Saharan Africa, and worldwide causes over 223,000 cases leading to more than 181,000 annual deaths. Usually, the fungus gets inhaled into the lungs where the initial interactions occur with pulmonary phagoc...

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Bibliographic Details
Main Authors: Benjamin N. Nelson, Cheyenne S. Daugherty, Rachel R. Sharp, J. Leland Booth, Vineet I. Patel, Jordan P. Metcalf, Kenneth L. Jones, Karen L. Wozniak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Cryptococcus
pulmonary phagocytes
macrophage subsets
dendritic cell subsets
pulmonary innate immunity
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054477/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054477/full

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