Macrophage-Myofibroblast Transition Contributes to Myofibroblast Formation in Proliferative Vitreoretinal Disorders

Macrophage-Myofibroblast Transition Contributes to Myofibroblast Formation in Proliferative Vitreoretinal Disorders

Inflammation and fibrosis are key features of proliferative vitreoretinal disorders. We aimed to define the macrophage phenotype and investigate the role of macrophage-myofibroblast transition (MMT) in the contribution to myofibroblast populations present in epiretinal membranes. Vitreous samples fr...

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Bibliographic Details
Main Authors: Ahmed M. Abu El-Asrar, Gert De Hertogh, Eef Allegaert, Mohd I. Nawaz, Sara Abouelasrar Salama, Priscilla W. Gikandi, Ghislain Opdenakker, Sofie Struyf
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
proliferative diabetic retinopathy
proliferative vitreoretinopathy
macrophage-myofibroblast transition
M2 macrophages
Online Access:https://www.mdpi.com/1422-0067/24/17/13510

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https://www.mdpi.com/1422-0067/24/17/13510

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