Safety and immunogenicity of heterologous COVID-19 vaccine regimens to deal with product shortage: A randomised clinical trial in an elderly population

Objectives: In a context of COVID-19 vaccine shortages, this study sought to evaluate the safety and efficacy of receiving one dose of Gam-COVID-Vac rAd26 followed by a second COVID-19 vaccine dose of either Gam-COVID-Vac rAd5, ChAdOx1 nCoV-19 or BBIBP-CorV in a cohort of older adults. Study design:...

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Main Authors: M.A. Kundro, M.H. Losso, A. Macchia, I. Pastor, M. Alonso Serena, C. Gestoso, L. Moreno Macías, F. Crupi, M.C. Acosta, S. Ivalo, M. Ghioldi, M.B. Bouzas, L. Mammana, I. Zapiola, I. Mazzitelli, A. Varese, J. Geffner, C. Biscayart, P. Angeleri, E. Lopez, A. Gentile, D. Ferrante, F. Gonzalez B. de Quiros
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Public Health in Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666535222000891