In silico, in vitro and in vivo analysis of binding affinity between N and C-domains of Clostridium perfringens alpha toxin.

In silico, in vitro and in vivo analysis of binding affinity between N and C-domains of Clostridium perfringens alpha toxin.

Clostridium perfringens alpha toxin/phospholipase C (CP-PLC) is one of the most potent bacterial toxins known to cause soft tissue infections like gas gangrene in humans and animals. It is the first bacterial toxin demonstrated to be an enzyme with phospholipase, sphingomyelinase and lecithinase act...

Full description

Bibliographic Details
Main Authors: Siva Ramakrishna Uppalapati, Joseph Jeyabalaji Kingston, Insaf Ahmed Qureshi, Harishchandra Sripathy Murali, Harsh Vardhan Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3859591?pdf=render

Internet

http://europepmc.org/articles/PMC3859591?pdf=render

Similar Items