Curcumin assists anti-EV71 activity of IFN-α by inhibiting IFNAR1 reduction in SH-SY5Y cells

Abstract Background and aim Enterovirus 71(EV71) can cause severe hand, foot, and mouth disease (HFMD) with brain tissue involvement. Few effective anti-EV71 drugs are presently available in clinical practice. Interferon-α (IFN-α) was ineffective while Curcumin was effective in restricting EV71 repl...

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Bibliographic Details
Main Authors: Yanfang Wang, Kena Dan, Xiaoling Xue, Bangtao Chen, Cheng Chen
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Gut Pathogens
Subjects:
Online Access:https://doi.org/10.1186/s13099-022-00481-5