Glutamate is required for depression but not potentiation of long-term presynaptic function

Hebbian plasticity is thought to require glutamate signalling. We show this is not the case for hippocampal presynaptic long-term potentiation (LTPpre), which is expressed as an increase in transmitter release probability (Pr). We find that LTPpre can be induced by pairing pre- and postsynaptic spik...

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Detalles Bibliográficos
Main Authors: Zahid Padamsey, Rudi Tong, Nigel Emptage
Formato: Artigo
Idioma:English
Publicado: eLife Sciences Publications Ltd 2017-11-01
Series:eLife
Subjects:
Acceso en liña:https://elifesciences.org/articles/29688