In Vitro Veritas: From 2D Cultures to Organ-on-a-Chip Models to Study Immunogenic Cell Death in the Tumor Microenvironment

In Vitro Veritas: From 2D Cultures to Organ-on-a-Chip Models to Study Immunogenic Cell Death in the Tumor Microenvironment

Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-cell-dependent anti-tumor immune response specific to antigens originating from dying cancer cells. Many anticancer agents and strategies induce ICD, but despite their robust effects in vitro and in vivo on mi...

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Bibliographic Details
Main Authors: Dmitri V. Krysko, Robin Demuynck, Iuliia Efimova, Faye Naessens, Olga Krysko, Elena Catanzaro
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
immunogenic cell death
tumor microenvironment
3D cell culture
spheroids
organoids
bioperfusion bioreactors
Online Access:https://www.mdpi.com/2073-4409/11/22/3705

Internet

https://www.mdpi.com/2073-4409/11/22/3705

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