Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation

Comprehensive computational analysis reveals YXXΦ[I/L/M/F/V] motif and YXXΦ-like tetrapeptides across HFRS causing Hantaviruses and their association with viral pathogenesis and host immune regulation

Hemorrhagic fever with renal syndrome (HFRS) is an acute zoonotic disease transmitted through aerosolized excrement of rodents. The etiology of HFRS is complex due to the involvement of viral factors and host immune and genetic factors. The viral species that dominantly cause HFRS are Puumala virus...

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Bibliographic Details
Main Authors: Fatima Noor, Usman Ali Ashfaq, Muhammad Asif, Muhammad Muzammal Adeel, Abdulrahman Alshammari, Metab Alharbi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
hemorrhagic fever with renal syndrome
hantavirus
YXXΦ[I/L/M/F/V] motif
YXXΦ-like tetrapeptides
3D structure
post-translational modifications
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1031608/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1031608/full

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