Stochastic dynamics of Francisella tularensis infection and replication.

We study the pathogenesis of Francisella tularensis infection with an experimental mouse model, agent-based computation and mathematical analysis. Following inhalational exposure to Francisella tularensis SCHU S4, a small initial number of bacteria enter lung host cells and proliferate inside them,...

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Bibliographic Details
Main Authors: Jonathan Carruthers, Grant Lythe, Martín López-García, Joseph Gillard, Thomas R Laws, Roman Lukaszewski, Carmen Molina-París
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007752