Uncovering the Effect and Mechanism of Rhizoma Corydalis on Myocardial Infarction Through an Integrated Network Pharmacology Approach and Experimental Verification

Uncovering the Effect and Mechanism of Rhizoma Corydalis on Myocardial Infarction Through an Integrated Network Pharmacology Approach and Experimental Verification

Background: Myocardial infarction (MI), characterized by reduced blood flow to the heart, is a coronary artery disorder with the highest morbidity and mortality among cardiovascular diseases. Consequently, there is an urgent need to identify effective drugs to treat MI. Rhizoma Corydalis (RC) is the...

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Bibliographic Details
Main Authors: Jingyan Li, Junxuan Wu, Junying Huang, Yuanyuan Cheng, Dawei Wang, Zhongqiu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
Corydalis yanhusuo
tetrahydropalmatine
myocardial infarction
network pharmacology
apoptosis
PI3k/Akt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.927488/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.927488/full

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