Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>Numerous epidemiological studies demonstrate that genetic background modifies the onset and the progression of Alzheimer's disease and related neurodegenerative disorders. The efficacious influence of genetic background on the d...

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Bibliographic Details
Main Authors: Kovacech Branislav, Novak Petr, Zilka Norbert, Stozicka Zuzana, Bugos Ondrej, Novak Michal
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/7/1/64