Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials.

Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials.

Despite the advent of long-acting anti-retroviral therapy able to control and prevent infection, a preventative vaccine remains a global priority for the elimination of HIV. The moderately protective RV144 vaccine trial suggested functional IgG1 and IgG3 antibodies were a potential correlate of prot...

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Bibliographic Details
Main Authors: Stephanie Fischinger, Deniz Cizmeci, Davy Deng, Shannon P Grant, Nicole Frahm, Julie McElrath, Jonathan Fuchs, Pierre-Alexandre Bart, Giuseppe Pantaleo, Michael Keefer, William O Hahn, Nadine Rouphael, Gavin Churchyard, Zoe Moodie, Yeycy Donastorg, Hendrik Streeck, Galit Alter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010016

Internet

https://doi.org/10.1371/journal.ppat.1010016

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