TNF-α/TNFR1 activated astrocytes exacerbate depression-like behavior in CUMS mice

Abstract Neuroinflammation is considered to be a significant mechanism contributing to depression. Several studies have reported that A1 astrocytes were highly prevalent in human neuroinflammatory and neurodegenerative diseases. However, the precise mechanism by which A1 astrocytes contribute to dep...

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Bibliographic Details
Main Authors: Mengjiao Gao, Yu Song, Yaqi Liu, Yuqing Miao, Yanwu Guo, Huihui Chai
Format: Article
Language:English
Published: Nature Publishing Group 2024-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01987-4