In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain
<p>Abstract</p> <p>Background</p> <p>Putatively active drugs are often intraventricularly administered to gain direct access to brain and circumvent the blood-brain barrier. A few studies on the normal central nervous system (CNS) have shown, however, that the distribut...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-07-01
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| Series: | Cerebrospinal Fluid Research |
| Online Access: | http://www.cerebrospinalfluidresearch.com/content/2/1/5 |