Effectiveness of an <i>O</i>-Alkyl Hydroxamate in Dogs with Naturally Acquired Canine Leishmaniosis: An Exploratory Clinical Trial

Effectiveness of an <i>O</i>-Alkyl Hydroxamate in Dogs with Naturally Acquired Canine Leishmaniosis: An Exploratory Clinical Trial

Canine leishmaniosis is a challenge in veterinary medicine and no drug to date has achieved parasite clearance in dogs. Histone deacetylase inhibitors are a drug class widely used in cancer chemotherapy. We have successfully used <i>O</i>-alkyl hydroxamates (vorinostat derivatives) in th...

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Bibliographic Details
Main Authors: Victoriano Corpas-López, Victoriano Díaz-Sáez, Francisco Morillas-Márquez, Francisco Franco-Montalbán, Mónica Díaz-Gavilán, Julián López-Viota, Margarita López-Viota, José Antonio Gómez-Vidal, Joaquina Martín-Sánchez
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Animals
Subjects:
vorinostat derivatives
canine leishmaniosis
treatment
<i>O</i>-alkyl hydroxamates
histone deacetylase inhibitors
effectiveness
Online Access:https://www.mdpi.com/2076-2615/12/19/2700

Internet

https://www.mdpi.com/2076-2615/12/19/2700

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