Synthesis and in silico screening of a library of β-carboline-containing compounds

Synthesis and in silico screening of a library of β-carboline-containing compounds

The synthesis of a library of tetrahydro-β-carboline-containing compounds in milligram quantities is described. Among the unique heterocyclic frameworks are twelve tetrahydroindolizinoindoles, six tetrahydrocyclobutanindoloquinolizinones and three tetrahydrocyclopentenoneindolizinoindolones. These c...

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Bibliographic Details
Main Authors: Kay M. Brummond, John R. Goodell, Matthew G. LaPorte, Lirong Wang, Xiang-Qun Xie
Format: Article
Language:English
Published: Beilstein-Institut 2012-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
β-carboline
biological activity
chemical diversity
diversity-oriented synthesis
in silico screening
Online Access:https://doi.org/10.3762/bjoc.8.117

Internet

https://doi.org/10.3762/bjoc.8.117

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