Distinct binding affinity of perfluoroalkyl acids to plant and animal proteins revealed by dialysis experiments, fluorescence spectroscopy, and QSAR modeling

Distinct binding affinity of perfluoroalkyl acids to plant and animal proteins revealed by dialysis experiments, fluorescence spectroscopy, and QSAR modeling

Understanding the binding dynamics between perfluoroalkyl acids (PFAAs) and proteins is crucial for risk assessment, as protein binding plays a vital role in the bioaccumulation of PFAAs. This study employed dialysis experiments to measure the protein-water partition coefficient of PFAAs with repres...

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Bibliographic Details
Main Authors: Yue Zhou, Yarui Liu, Xiaojia Yuan, Yuefei Ruan, Hao Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Perfluoroalkyl acids
Protein-water partition coefficient
Bioaccumulation capacity
Quantitative structure-activity relationship model
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325002386

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http://www.sciencedirect.com/science/article/pii/S0147651325002386

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