Novel Brown Coat Color (Cocoa) in French Bulldogs Results from a Nonsense Variant in <i>HPS3</i>

Novel Brown Coat Color (Cocoa) in French Bulldogs Results from a Nonsense Variant in <i>HPS3</i>

Brown or chocolate coat color in many mammalian species is frequently due to variants at the B locus or <i>TYRP1</i> gene. In dogs, five different <i>TYRP1</i> loss-of-function alleles have been described, which explain the vast majority of dogs with brown coat color. Recentl...

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Bibliographic Details
Main Authors: Sarah Kiener, Alexandra Kehl, Robert Loechel, Ines Langbein-Detsch, Elisabeth Müller, Danika Bannasch, Vidhya Jagannathan, Tosso Leeb
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Genes
Subjects:
dog
<i>Canis lupus familiaris</i>
whole genome sequence
wgs
heterogeneity
melanosome
Online Access:https://www.mdpi.com/2073-4425/11/6/636

Internet

https://www.mdpi.com/2073-4425/11/6/636

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