Aspects of innate immunity and Parkinson’s disease

Aspects of innate immunity and Parkinson’s disease

Genetic studies on PARK genes have identified dysfunction in proteasomal, lysosomal and mitochondrial enzymes as pathogenic for Parkinson’s disease (PD). We review the role of these and similar enzymes in mediating innate immune signalling. In particular, we have identified that a number of PARK gen...

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Bibliographic Details
Main Authors: Yue eHuang, Glenda Margaret Halliday
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Pharmacology
Subjects:
Immunity
Ubiquitination
Parkinson’s disease
Mitochondrial dysfunction
synapse dysfunction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00033/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00033/full

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