Shared gene characteristics and molecular mechanisms of macrophages M1 polarization in calcified aortic valve disease

BackgroundCAVD is a common cardiovascular disease, but currently there is no drug treatment. Therefore, it is urgent to find new and effective drug therapeutic targets. Recent evidence has shown that the infiltration of M1 macrophages increased in the calcified aortic valve tissues, but the mechanis...

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Bibliographic Details
Main Authors: Ming Qin, Qian Chen, Ning Li, Xiangyang Xu, Chuyi Wang, Guokun Wang, Zhiyun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1058274/full