Human induced hepatic lineage-oriented stem cells: autonomous specification of human iPS cells toward hepatocyte-like cells without any exogenous differentiation factors.
Preparing targeted cells for medical applications from human induced pluripotent stem cells (hiPSCs) using growth factors, compounds, or gene transfer has been challenging. Here, we report that human induced hepatic lineage-oriented stem cells (hiHSCs) were generated and expanded as a new type of hi...
Main Authors: | Tetsuya Ishikawa, Momoko Kobayashi, Satoshi Yanagi, Chika Kato, Ryokichi Takashima, Eiji Kobayashi, Keitaro Hagiwara, Takahiro Ochiya |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4395359?pdf=render |
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