Acceleration and suppression of resistance development by antibiotic combinations

Abstract Background The emergence and spread of antibiotic resistance in bacteria is becoming a global public health problem. Combination therapy, i.e., the simultaneous use of multiple antibiotics, is used for long-term treatment to suppress the emergence of resistant strains. However, the effect o...

Full description

Bibliographic Details
Main Authors: Shingo Suzuki, Takaaki Horinouchi, Chikara Furusawa
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-017-3718-2