Long-Term Sertraline Intake Reverses the Behavioral Changes Induced by Prenatal Stress in Rats in a Sex-Dependent Way

Long-Term Sertraline Intake Reverses the Behavioral Changes Induced by Prenatal Stress in Rats in a Sex-Dependent Way

Early life stress is a major factor underlying the vulnerability to respond to stressful events later in life. The present study attempted to evaluate the role of prenatal stress affecting the development of stress-related disorders and their reversion by postnatal exposure to Sertraline (SERT), a f...

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Bibliographic Details
Main Authors: Inês Pereira-Figueiredo, Orlando Castellano, Adelaida S. Riolobos, Graça Ferreira-Dias, Dolores E. López, Consuelo Sancho
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
antidepressant treatment
early stress
fear conditioning
footshock
prepulse inhibition
sex differences
Online Access:http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00099/full

Internet

http://journal.frontiersin.org/article/10.3389/fnbeh.2017.00099/full

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