Development and Evaluation of Lyophilized Methotrexate Nanosuspension using Quality by Design Approach
With the application of the quality by design (QbD) approach, a high-pressure homogenizer (HPH) methodology was employed to develop methotrexate nanosuspension (MTX-NS) to boost bioavailability. The Ishikawa diagram was used to analyze potential risk factors in formulation development. To screen and...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Slovenian Chemical Society
2021-12-01
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Series: | Acta Chimica Slovenica |
Subjects: | |
Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/6858 |