Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions

In mammalian cell lines, Cep55 protein recruits the endosomal sorting complex required for transport (ESCRT) and promotes the completion of cell division. Here, the authors show that Cep55-knockout mice are viable and primary fibroblasts cultured in vitro divide in a Cep55 and ESCRT-independent way.

Bibliographic Details
Main Authors: Antonio Tedeschi, Jorge Almagro, Matthew J. Renshaw, Hendrik A. Messal, Axel Behrens, Mark Petronczki
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15359-w

Internet

https://doi.org/10.1038/s41467-020-15359-w

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