CRISPR/Cas12a-Based Ultrasensitive and Rapid Detection of <i>JAK2</i> V617F Somatic Mutation in Myeloproliferative Neoplasms

CRISPR/Cas12a-Based Ultrasensitive and Rapid Detection of <i>JAK2</i> V617F Somatic Mutation in Myeloproliferative Neoplasms

The <i>J</i><i>AK2</i> V617F mutation is a major diagnostic, therapeutic, and monitoring molecular target of Philadelphia-negative myeloproliferative neoplasms (MPNs). To date, numerous methods of detecting the <i>JAK2</i> V617F mutation have been reported, but th...

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Bibliographic Details
Main Authors: Miaomiao Chen, Chunhua Zhang, Zhiqing Hu, Zhuo Li, Menglin Li, Lingqian Wu, Miaojin Zhou, Desheng Liang
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biosensors
Subjects:
<i>JAK2</i> V617F
CRISPR/Cas12a
mutation detection
fluorescence detection system
lateral flow strip
Philadelphia-negative myeloproliferative neoplasms
Online Access:https://www.mdpi.com/2079-6374/11/8/247

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https://www.mdpi.com/2079-6374/11/8/247

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