Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Inhibits RNA-Mediated Gene Silencing by Targeting Ago-2

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Inhibits RNA-Mediated Gene Silencing by Targeting Ago-2

Porcine reproductive and respiratory syndrome virus (PRRSV) infection strongly modulates the host’s immune response. The RNA silencing pathway is an intracellular innate response to viral infections. However, it is unknown whether PRRSV interacts with cellular RNA silencing to facilitate the viral i...

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Bibliographic Details
Main Authors: Jing Chen, Xibao Shi, Xiaozhuan Zhang, Li Wang, Jun Luo, Guangxu Xing, Ruiguang Deng, Hong Yang, Jinting Li, Aiping Wang, Gaiping Zhang
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Viruses
Subjects:
porcine reproductive and respiratory syndrome virus (PRRSV)
RNA silencing
non-structure protein 1α (nsp1α)
nsp11
Ago-2
Online Access:http://www.mdpi.com/1999-4915/7/10/2893

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http://www.mdpi.com/1999-4915/7/10/2893

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