Studying the Geroprotective Properties of YAP/TAZ Signaling Inhibitors on <i>Drosophila melanogaster</i> Model

The transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the main downstream effectors of the evolutionarily conserved Hippo signaling pathway. YAP/TAZ are implicated in the transcriptional regulation of target genes that are invo...

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Bibliographic Details
Main Authors: Denis A. Golubev, Nadezhda V. Zemskaya, Anastasia A. Gorbunova, Daria V. Kukuman, Alexey Moskalev, Mikhail V. Shaposhnikov
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/6/6006