Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone

Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone

The present study aims to investigate if Cimicifuga racemosa (L.) Nutt extract (CIMI) reduces deleterious effects of dexamethasone (DEXA) in ovaries cultured in vitro. Mouse ovaries were collected and cultured in DMEM+ only or supplemented with 5 ng/mL of CIMI, or 4 ng/mL DEXA, or both CIMI and DEXA...

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Bibliographic Details
Main Authors: E.I.T. de Assis, V.A.N. Azevedo, M.F. de Lima Neto, F.C. Costa, L.R.F.M. Paulino, P.A.A. Barroso, M.H.T. Matos, A.P.O. do Monte, M.A.M. Donato, C.A. Peixoto, A.N. Godinho, J.M.O. Freire, A.L.P. Souza, J.R.V. Silva, A.W.B. Silva
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2023-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Folliculogenesis
Toxicity
Mice
Glucocorticoid
In vitro culture
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100667&tlng=en

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