A micro-sized vaccine based on recombinant Lactiplantibacillus plantarum fights against SARS-CoV-2 infection via intranasal immunization

A micro-sized vaccine based on recombinant Lactiplantibacillus plantarum fights against SARS-CoV-2 infection via intranasal immunization

COVID-19 has globally spread to burden the medical system. Even with a massive vaccination, a mucosal vaccine offering more comprehensive and convenient protection is imminent. Here, a micro-sized vaccine based on recombinant Lactiplantibacillus plantarum (rLP) displaying spike or receptor-binding d...

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Bibliographic Details
Main Authors: Letian Li, Jiayi Hao, Yuhang Jiang, Pengfei Hao, Yuwei Gao, Jing Chen, Guoqing Zhang, Ningyi Jin, Maopeng Wang, Chang Li
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Acta Pharmaceutica Sinica B
Subjects:
COVID-19
Mucosal vaccines
Lactiplantibacillus plantarum
Microparticle
Intranasal administration
Viral challenge
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000059

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http://www.sciencedirect.com/science/article/pii/S2211383523000059

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