Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients

Prevalence of RECQL germline variants in Pakistani early-onset and familial breast cancer patients

Abstract Background The RecQ Like Helicase (RECQL) gene has previously been shown to predispose to breast cancer mainly in European populations, in particular to estrogen receptor (ER) and/or progesterone receptor (PR) positive tumor. Here, we investigated the contribution of pathogenic RECQL germli...

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Bibliographic Details
Main Authors: Muhammad Usman Rashid, Noor Muhammad, Faiz Ali Khan, Umara Shehzad, Humaira Naeemi, Naila Malkani, Ute Hamann
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
RECQL
Germline variants
Breast cancer
Pakistan
Online Access:https://doi.org/10.1186/s13053-020-00159-6

Internet

https://doi.org/10.1186/s13053-020-00159-6

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