The Impact of the CTHRSSVVC Peptide Upon Experimental Models of Trypanosoma cruzi Infection

The Impact of the CTHRSSVVC Peptide Upon Experimental Models of Trypanosoma cruzi Infection

Chagas disease (CD), caused by the hemoflagellate protozoan Trypanosoma cruzi, affects more than six million people worldwide and presents an unsatisfactory therapy, based on two nitroderivatives, introduced in clinical medicine for decades. The synthetic peptide, with CTHRSSVVC sequence (PepA), mim...

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Bibliographic Details
Main Authors: Gabriela Rodrigues Leite, Denise da Gama Jaén Batista, Ana Lia Mazzeti, Rosemeire Aparecida Silva, Ademar Benévolo Lugão, Maria de Nazaré Correia Soeiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chagas disease
Trypanosoma cruzi
experimental chemotherapy
CTHRSSVVC peptide
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.882555/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.882555/full

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