The role of PTEN - HCV core interaction in hepatitis C virus replication

Abstract Hepatitis C virus (HCV) infection leads to severe liver diseases including hepatocellular carcinoma (HCC). Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a tumour suppressor, is frequently mutated or deleted in HCC tumors. PTEN has previously been demonstrated to inhibit HC...

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Bibliographic Details
Main Authors: Qi Wu, Zhubing Li, Paul Mellor, Yan Zhou, Deborah H. Anderson, Qiang Liu
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03052-w