Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

Abstract Glioblastoma (GBM) is the most frequent malignant brain tumor, the relapse of which is unavoidable following standard treatment. However, the effective treatment for recurrent GBM is lacking, necessitating the understanding of key mechanisms driving tumor recurrence and the identification o...

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Bibliographic Details
Main Authors: Xin Wang, Qian Sun, Weiwen Wang, Baohui Liu, Ying Gu, Liang Chen
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Acta Neuropathologica Communications
Subjects:
Glioblastoma
Recurrence
scRNA-seq
MAFK
NFATC4
Tumor microenvironment
Online Access:https://doi.org/10.1186/s40478-023-01613-x

Internet

https://doi.org/10.1186/s40478-023-01613-x

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