Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1

Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1

Epigenetic readout of the combinatorial posttranslational modification comprised of trimethyllysine and asymmetric dimethylarginine (H3K4me3R8me2a) takes place via biomolecular recognition of tandem Tudor-domain-containing protein Spindlin1. Through comparative thermodynamic data and molecular dynam...

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Bibliographic Details
Main Authors: Miriam R. B. Porzberg, Laust Moesgaard, Catrine Johansson, Udo Oppermann, Jacob Kongsted, Jasmin Mecinović
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
epigenetics
histone
arginine methylation
molecular recognition
reader protein
Online Access:https://www.mdpi.com/1420-3049/27/3/983

Internet

https://www.mdpi.com/1420-3049/27/3/983

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