Previous Infection Combined with Vaccination Produces Neutralizing Antibodies with Potency against SARS-CoV-2 Variants

Previous Infection Combined with Vaccination Produces Neutralizing Antibodies with Potency against SARS-CoV-2 Variants

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve in humans. Spike protein mutations increase transmission and potentially evade antibodies raised against the original sequence used in current vaccines. Our evaluation of serum neutralizing activity in both per...

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Bibliographic Details
Main Authors: F. Javier Ibarrondo, Christian Hofmann, Ayub Ali, Paul Ayoub, Donald B. Kohn, Otto O. Yang
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mBio
Subjects:
SARS-CoV-2
COVID-19
vaccines
humoral immunity
spike variants
vaccine efficacy
Online Access:https://journals.asm.org/doi/10.1128/mBio.02656-21

Internet

https://journals.asm.org/doi/10.1128/mBio.02656-21

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