Akt: A Therapeutic Target in Hepatic Ischemia–Reperfusion Injury

Background: Liver transplantation is the second most common transplant procedure in the United States. A leading cause of post-transplantation organ dysfunction is I/R injury. During I/R injury, the serine/threonine kinase Akt is activated, stimulating downstream mediators to promote cellular surviv...

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Bibliographic Details
Main Authors: Stephen M. Covington, Laura D. Bauler, Luis H. Toledo-Pereyra
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Investigative Surgery
Subjects:
Online Access:http://dx.doi.org/10.1080/08941939.2016.1206999