Astaxanthin Attenuates Early Acute Kidney Injury Following Severe Burns in Rats by Ameliorating Oxidative Stress and Mitochondrial-Related Apoptosis

Astaxanthin Attenuates Early Acute Kidney Injury Following Severe Burns in Rats by Ameliorating Oxidative Stress and Mitochondrial-Related Apoptosis

Early acute kidney injury (AKI) is a devastating complication in critical burn patients, and it is associated with severe morbidity and mortality. The mechanism of AKI is multifactorial. Astaxanthin (ATX) is a natural compound that is widely distributed in marine organisms; it is a strong antioxidan...

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Bibliographic Details
Main Authors: Song-Xue Guo, Han-Lei Zhou, Chun-Lan Huang, Chuan-Gang You, Quan Fang, Pan Wu, Xin-Gang Wang, Chun-Mao Han
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Marine Drugs
Subjects:
astaxanthin
acute kidney injury
burn
oxidative stress
apoptosis
mitochondria
Online Access:http://www.mdpi.com/1660-3397/13/4/2105

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http://www.mdpi.com/1660-3397/13/4/2105

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