HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP.
Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in approximately 5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load (proportion of infected mononuclear cells in the c...
| Κύριοι συγγραφείς: | , , , , |
|---|---|
| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Public Library of Science (PLoS)
2008-03-01
|
| Σειρά: | PLoS Pathogens |
| Διαθέσιμο Online: | http://europepmc.org/articles/PMC2265437?pdf=render |