HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP.

HTLV-1 integration into transcriptionally active genomic regions is associated with proviral expression and with HAM/TSP.

Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in approximately 5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected people, even at the same proviral load (proportion of infected mononuclear cells in the c...

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Bibliografische gegevens
Hoofdauteurs: Kiran N Meekings, Jeremy Leipzig, Frederic D Bushman, Graham P Taylor, Charles R M Bangham
Formaat: Artikel
Taal:English
Gepubliceerd in: Public Library of Science (PLoS) 2008-03-01
Reeks:PLoS Pathogens
Online toegang:http://europepmc.org/articles/PMC2265437?pdf=render

Internet

http://europepmc.org/articles/PMC2265437?pdf=render

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