ac4C acetylation regulates mRNA stability and translation efficiency in osteosarcoma

ac4C acetylation regulates mRNA stability and translation efficiency in osteosarcoma

Objective: N4-acetylcytidine (ac4C) acetylation can promote target gene expression through improved mRNA stability. To explore the role of ac4C acetylation in osteosarcoma, U2OS and MG63 cell lines were treated with the N-acetyltransferase 10 (NAT10) inhibitor Remodelin. Reverse transcription–polyme...

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Bibliographic Details
Main Authors: Wenjie Zhang, Jia Gao, Lei Fan, Juan Wang, Bin He, Yunhua Wang, Xiaotong Zhang, Hui Mao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
ac4C acetylation
NAT10
Osteosarcoma
acRIP-seq
FNTB gene
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023043116

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http://www.sciencedirect.com/science/article/pii/S2405844023043116

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