A sequence-based evolutionary distance method for Phylogenetic analysis of highly divergent proteins

Abstract Because of the limited effectiveness of prevailing phylogenetic methods when applied to highly divergent protein sequences, the phylogenetic analysis problem remains challenging. Here, we propose a sequence-based evolutionary distance algorithm termed sequence distance (SD), which innovativ...

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Bibliographic Details
Main Authors: Wei Cao, Lu-Yun Wu, Xia-Yu Xia, Xiang Chen, Zhi-Xin Wang, Xian-Ming Pan
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47496-9