Small Angle X-ray Scattering Sensing Membrane Composition: The Role of Sphingolipids in Membrane-Amyloid β-Peptide Interaction

The early impairments appearing in Alzheimer’s disease are related to neuronal membrane damage. Both aberrant Aβ species and specific membrane components play a role in promoting aggregation, deposition, and signaling dysfunction. Ganglioside GM1, present with cholesterol and sphingomyelin in lipid...

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Bibliographic Details
Main Authors: Rita Carrotta, Maria Rosalia Mangione, Fabio Librizzi, Oscar Moran
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/1/26