Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA

Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA

The indolocarbazole (ICZ) alkaloids have attracted much attention due to their unique structures and potential therapeutic applications. A series of ICZs were recently isolated and identified from a marine-derived actinomycete strain, Streptomyces sanyensis FMA. To elucidate the biosynthetic machine...

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Bibliographic Details
Main Authors: Wenli Li, Kui Hong, Weiming Zhu, Jingtao Zhang, Qiu Cui, Yuanyuan Du, Tong Li
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Marine Drugs
Subjects:
indolocarbazole (ICZ)
biosynthesis
heterologous expression
Streptomyces sanyensis FMA
Online Access:http://www.mdpi.com/1660-3397/11/2/466

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http://www.mdpi.com/1660-3397/11/2/466

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