i-Modern: Integrated multi-omics network model identifies potential therapeutic targets in glioma by deep learning with interpretability

i-Modern: Integrated multi-omics network model identifies potential therapeutic targets in glioma by deep learning with interpretability

Effective and precise classification of glioma patients for their disease risks is critical to improving early diagnosis and patient survival. In the recent past, a significant amount of multi-omics data derived from cancer patients has emerged. However, a robust framework for integrating multi-omic...

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Bibliographic Details
Main Authors: Xingxin Pan, Brandon Burgman, Erxi Wu, Jason H. Huang, Nidhi Sahni, S. Stephen Yi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Multi-omics
Deep learning model
Data integration
Patient stratification
Glioma
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002720

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http://www.sciencedirect.com/science/article/pii/S2001037022002720

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