Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

Summary: Interleukin (IL)-10 is a main player in peripheral immune tolerance, the physiological mechanism preventing immune reactions to self/harmless antigens. Here, we investigate IL-10-induced molecular mechanisms generating tolerogenic dendritic cells (tolDC) from monocytes. Using genomic studie...

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Bibliographic Details
Main Authors: Daniele Avancini, Alessandro Testori, Lucia Fresolone, Grazia Andolfi, Michela Vuono, Vittorio Martinelli, Francesca R. Santoni de Sio, Silvia Gregori
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002048

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http://www.sciencedirect.com/science/article/pii/S2211124723002048

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