Targeting fructose metabolism by glucose transporter 5 regulation in human cholangiocarcinoma

Targeting fructose metabolism by glucose transporter 5 regulation in human cholangiocarcinoma

Alterations in cellular metabolism may contribute to tumor proliferation and survival. Upregulation of the facilitative glucose transporter (GLUT) plays a key role in promoting cancer. GLUT5 mediates modulation of fructose utilization, and its overexpression has been associated with poor prognosis i...

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Bibliographic Details
Main Authors: Nattawan Suwannakul, Napat Armartmuntree, Raynoo Thanan, Kaoru Midorikawa, Tetsuo Kon, Shinji Oikawa, Hatasu Kobayashi, Ning Ma, Shosuke Kawanishi, Mariko Murata
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-11-01
Series:Genes and Diseases
Subjects:
Cholangiocarcinoma
Fructose
Glucose transporter 5
Metabolic regulation
Warburg effect
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304221001100

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http://www.sciencedirect.com/science/article/pii/S2352304221001100

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