Youth Depression Alleviation with Anti-inflammatory Agents (YoDA-A): a randomised clinical trial of rosuvastatin and aspirin

Youth Depression Alleviation with Anti-inflammatory Agents (YoDA-A): a randomised clinical trial of rosuvastatin and aspirin

Abstract Background Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies might therefore have therapeutic potential. This trial aimed to determine whether adjunctive aspirin or rosuvastatin, compared with placebo, reduced depressive sym...

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Bibliographic Details
Main Authors: Michael Berk, Mohammadreza Mohebbi, Olivia M. Dean, Sue M. Cotton, Andrew M. Chanen, Seetal Dodd, Aswin Ratheesh, G. Paul Amminger, Mark Phelan, Amber Weller, Andrew Mackinnon, Francesco Giorlando, Shelley Baird, Lisa Incerti, Rachel E. Brodie, Natalie O. Ferguson, Simon Rice, Miriam R. Schäfer, Edward Mullen, Sarah Hetrick, Melissa Kerr, Susy M. Harrigan, Amelia L. Quinn, Catherine Mazza, Patrick McGorry, Christopher G. Davey
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Medicine
Subjects:
Depression
Treatment
Statins
Online Access:https://doi.org/10.1186/s12916-019-1475-6

Internet

https://doi.org/10.1186/s12916-019-1475-6

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