Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae

Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae

Quorum sensing (QS) is a cell–cell communication mechanism that enables bacteria to assess their population density and alter their behavior upon reaching high cell number. Many bacterial pathogens utilize QS to initiate an attack on their host, thus QS has attracted significant attention as a poten...

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Bibliographic Details
Main Authors: Bimal Koirala, Robert A. Hillman, Erin K. Tiwold, Michael A. Bertucci, Yftah Tal-Gan
Format: Article
Language:English
Published: Beilstein-Institut 2018-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
binding surface
competence stimulating peptide (CSP)
protein–peptide interactions
quorum sensing
Streptococcus pneumoniae
structure–activity relationships (SAR)
Online Access:https://doi.org/10.3762/bjoc.14.151

Internet

https://doi.org/10.3762/bjoc.14.151

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